Xiuren Zhang

METTL14-dependent m6A modification restrains interferon signaling to prevent myocarditis and dilated Cardiomyopathy

This study shows that METTL14-dependent m6A modification prevents myocarditis and dilated cardiomyopathy by restraining IFN signaling and necroptosis in cardiomyocytes.

A specialized ARGONAUTE enables trans-species RNA interference in plant immunity

This study identifies AGO10 as a key player in trans-species RNA interference in plant immunity, showing its role in pathogen gene silencing and immune response.

The spliceosome component U1-70k loads nascent transcripts onto FVE/SGS3 via co-condensation to embark on RNA silencing

The paper identifies U1-70k as a novel spliceosome factor that facilitates RNA silencing by co-condensing with SGS3 to load nascent transcripts into the PTGS pathway.

Reciprocal regulation of m6A modification and miRNA production machineries via phase separation-dependent and -independent mechanisms

Loss of H3.1K27me1 in Arabidopsis confers resistance to Geminivirus by sequestering DNA repair proteins onto rDNA and defense-related genes

This study shows that loss of H3.1K27me1 in Arabidopsis leads to resistance against Geminivirus by sequestering DNA repair proteins to defense genes and rDNA, reducing viral replication.