Gabriella T. Heller

SpinForecast: chain-free probabilistic backbone assignment of intrinsically disordered proteins from NMR chemical shifts

SpinForecast assigns residue-specific chemical shifts to disordered proteins without sequential chain building, achieving high accuracy in peak assignment for three test proteins.

Liquid liquid phase separation of the intrinsically disordered protein JPT2compartmentalizes components of NAADP-evoked Ca2+ signaling

This study shows JPT2, an intrinsically disordered NAADP-binding protein, undergoes liquid-liquid phase separation, forming condensates that recruit components involved in NAADP-evoked Ca2+ signaling.

Methylthio-alkane reductases use nitrogenase metalloclusters for carbon-sulfur bond cleavage

This study presents the first molecular structure of methylthio-alkane reductase, revealing metalloclusters that inform its function and evolutionary relationship to nitrogenases.

An integrative characterisation of proline cis and trans conformers in a disordered peptide

This paper uses MD simulations, NMR, and SAXS to characterise the cis and trans proline conformations of ORF6CTR from SARS-CoV-2, showing good agreement between simulations and experiments.

Micromolar fluoride contamination arising from glass NMR tubes and a simple solution for biomolecular applications

The paper identifies fluoride contamination from glass NMR tubes and proposes a simple solution to mitigate it in biomolecular applications.