Author

Nea Korvenlaita

University of Eastern FinlandORCID 0000-0002-7982-7654Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Irene F. UgidosiD· 2 shared Jari KoıstınahoiD· 2 shared Luca GiudiceiD· 2 shared Mireia Gómez‐BudiaiD· 2 shared Paula KorhoneniD· 2 shared Rashid A. GiniatulliniD· 2 shared Tarja MalmiD· 2 shared Alice PébayiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersMolecular Biology

Irene F. UgidosORCID

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2 papers

Recent·Most cited

ciRS-7 and miR7 regulate ischemia induced neuronal death via glutamatergic signaling

Flavia Scoyni, Valeriia Sitnikova, Luca Giudice, Paula Korhonen, Davide M Trevisan, Ana Hernández de Sande, Mireia Gómez‐Budia, Raisa Giniatullina, Irene F. Ugidos, Hiramani Dhungana, Cristiana Pistono, Nea Korvenlaita, Nelli‐Noora Välimäki, Salla M. Kangas, Anniina E. Hiltunen, , Tarja Malm

The paper shows that ciRS-7 and miR-7 regulate ischemia-induced neuronal death through glutamatergic signaling in mice.

Cell Reports · Mar 1, 2024Peer-reviewedMolecular Biology

Microglial amyloid beta clearance is driven by PIEZO1 channels

Henna Konttinen, Valeria Sitnikova, Yevheniia Ishchenko, Anastasia Shakirzyanova, Luca Giudice, Irene F. Ugidos, Mireia Gómez‐Budia, Nea Korvenlaita, Sohvi Ohtonen, Irina Belaya, Mohammad Feroze Fazaludeen, Nikita Mikhailov, Maria Gotkiewicz, Kirsi Ketola, Šárka Lehtonen, , Tarja Malm

This study shows that activating PIEZO1 channels in microglia improves amyloid beta clearance in AD models by enhancing survival, phagocytosis, and lysosomal activity.

bioRxiv · Mar 18, 2022 · PreprintNeuroscience