Author
University of Eastern FinlandORCID 0000-0003-4674-6484Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Hong Yan, Yashvi Bhat, Polina Malahov…·Amalia M. Dolga
This study shows diesel exhaust particles impair microglial function and amyloid-beta clearance in both mouse and human models, potentially contributing to Alzheimer's disease progression.
Tanja Hyvärinen, Johanna Lotila, Luca Giudice…·Sanna Hagman
This study shows that microglia from MS patients have intrinsic activation features, identified through iPSC-derived microglia-like cells and transcriptomic analysis.
Hannah Rostalski, Tomi Hietanen, Dorit B. Hoffmann…·Annakaisa Haapasalo
This study shows that C9orf72 repeat expansion in iPSC-derived microglia from FTD patients leads to increased phagocytic activity and reduced autophagosomal-lysosomal vesicles.
Zengjie Xia, Emily E. Prescott, Agnieszka N. Urbanek…·Suman De
The paper shows that apoE isoforms modulate Aβ aggregation, clearance, and toxicity in Alzheimer's disease, with implications for therapeutic strategies.
Henna Konttinen, Valeria Sitnikova, Yevheniia Ishchenko…·Tarja Malm
This study shows that activating PIEZO1 channels in microglia improves amyloid beta clearance in AD models by enhancing survival, phagocytosis, and lysosomal activity.
Ilkka Fagerlund, Antonios Dougalis, Anastasia Shakirzyanova…·Tarja Malm
This study shows that incorporating microglial progenitors into human brain organoids supports neuronal maturation and synaptic activity.