Author

Lucas Alvizi

Universidade de São PauloORCID 0000-0002-8058-6261Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Maria Rita Passos-BuenoiD· 3 shared Bárbara Bischain· 1 shared Beaté St PourcainiD· 1 shared Camila Bassi Fernandes da Silva· 1 shared Caroline Laura ReltoniD· 1 shared Chao Yun Irene YaniD· 1 shared Diogo Andrade NaniiD· 1 shared Elisabeth MangoldiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersDevelopmental Biology

Maria Rita Passos-BuenoORCID

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Author profile →

4 papers

Recent·Most cited

Reciprocal mechanochemical feedback couples neural crest migration and neurulation

Kai Weißenbruch, Lucas Alvizi, Jemima J. Burden, Roberto Mayor

This study shows that neural crest migration and neurulation are functionally coupled through reciprocal mechanochemical feedback, with MMP14-mediated extracellular matrix remodeling playing a key role.

bioRxiv · Aug 17, 2026 · PreprintDevelopmental Biology

Maternal-fetal inflammation affects Cdh1/E-cadherin epigenetic regulation and craniofacial development

Diogo Andrade Nani, Lucas Alvizi, Heloisa Maria de Siqueira Bueno, Ellen Cristina Miranda Lacerda, Chao Yun Irene Yan, Maria Rita Passos-Bueno

The paper investigates how maternal pro-inflammatory responses affect Cdh1/E-cadherin epigenetic regulation and craniofacial development in embryos.

bioRxiv · Sep 27, 2025 · PreprintDevelopmental Biology

"mir152 hypomethylation, potentially triggered by embryonic hypoxia, as a mechanism for non-syndromic cleft lip/palate"

Lucas Alvizi, Luciano Abreu Brito, Bárbara Bischain, Camila Bassi Fernandes da Silva, Sofia Lígia Guimarães Ramos, Gerson Shigeru Kobayashi, Jaqueline Yu Ting Wang, Maria Rita Passos‐Bueno

The paper identifies mir152 hypomethylation as a potential mechanism for non-syndromic cleft lip/palate, linked to embryonic hypoxia in zebrafish models.

bioRxiv · Nov 22, 2019 · PreprintDevelopmental Biology

DNA methylation mediates genetic liability to non-syndromic cleft lip/palate

Laurence J Howe, Tom G. Richardson, Ryan Arathimos, Lucas Alvizi, Maria Rita Passos‐Bueno, Philip Stanier, Ellen Aagaard Nohr, Kerstin U. Ludwig, Elisabeth Mangold, Michael Knapp, Evie Stergiakouli, Beaté St Pourcain, George Davey Smith, Jonathan R. Sandy, Caroline Laura Relton, , Gemma C. Sharp

The paper identifies three loci where genetic liability to non-syndromic cleft lip/palate may be mediated by DNA methylation variation in blood and tissue.

Epigenomics · Jan 14, 2019Peer-reviewedGenetics