Author

Sandeep K. Singh

Virginia Commonwealth UniversityORCID 0000-0002-8069-6452Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Tomasz KordulaiD· 2 shared A. Rory McQuiston· 1 shared Amandeep GirdhariD· 1 shared Amy L. OlexiD· 1 shared Angela Satya GuptaiD· 1 shared Avani Hariprashad· 1 shared Babette FussiD· 1 shared Basant Kumar PateliD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersNeuroscience

Tomasz KordulaORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 14, 2026

Astrocyte-oligodendrocyte crosstalk dependent myelination via secreted protein YKL40

Oscar Dominguez, Soha Munir, Surya Chandra Rao Thumu…·Sandeep K. Singh

This study identifies YKL40 as a secreted protein mediating astrocyte-OPC communication to drive myelination during brain development.

DOI 10.64898/2026.09.08.750142

mousebulk RNA-seq

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NeurosciencebioRxivPreprintMar 28, 2022

Sparcl1/Hevin drives inflammatory and neuropathic pain through astrocyte and NMDA receptor signaling

Gang Chen, Hao Luo, Xin Luo…·Ru‐Rong Ji

This study shows hevin, an astrocyte-secreted protein, maintains chronic pain through NMDA receptor signaling, and neutralizing hevin may offer new therapeutic strategies for pain and neurodegeneration.

DOI 10.1101/2022.03.28.486142

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 14, 2021

Yin Yang 1 sets up the stage for cerebellar astrocyte maturation

Karli Mockenhaupt, Katarzyna M. Tyc, A. Rory McQuiston…·Tomasz Kordula

This study identifies YY1's role in regulating cerebellar astrocyte maturation and maintenance in adult mice through single-cell RNA-seq analysis.

1 citation

mousebulk RNA-seq

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BioinformaticsInternational Journal of Biological MacromoleculesPeer-reviewedJan 7, 2020

Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-432C-A315T by AIM4.

Amandeep Girdhar, Vidhya Bharathi, Vikas Ramyagya Tiwari…·Basant Kumar Patel

This study uses computational methods to identify AIM4's binding site on TDP-43 and shows it inhibits LLPS of a TDP-43 mutant in vitro.

56 citations

protein structurestatistical model

𝕏 PostBluesky