Kelly A. Ruhn

Salmonella lipopolysaccharide stimulates uptake of long-chain fatty acids in the small intestine

This study shows Salmonella LPS enhances fatty acid uptake in the mouse intestine via CD36 and myeloid TLR4, linking microbial sensing to lipid absorption and host defense.

The gut microbiota directs vitamin A flux to regulate intestinal T cell development

This paper shows the gut microbiota regulates intestinal T cell development by directing vitamin A flux through a sequential pathway involving epithelial, myeloid, and T cells.

B3GNT7 regulates mucin glycosylation and protects against colitis and infection

This study shows B3GNT7 regulates colonic mucus glycosylation, protects against colitis and infection, and has a distinct function from other B3GNT family members.

Translational control of innate barrier defense by the gut microbiota

The gut microbiota enhances translation of innate barrier defense proteins through HDAC5-mediated activation of mTORC1 signaling.