Deborah S. Wuttke

The paper shows that telomerase elongates a second substrate formed by spontaneous replication fork collapse in budding yeast, significantly contributing to telomere length homeostasis.

This paper identifies the MBD-ID module as a unified DNA/RNA binding interface in MECP2, showing it is disrupted in Rett syndrome due to mutations in the intervening domain.

This study identifies a distinct mechanism of RNA recognition by GATA1, showing competitive DNA/RNA binding through an overlapping surface involving the ARM-like domain.

This study investigates the DNA and RNA binding kinetics of ERα and Sox2, revealing distinct multiphasic binding mechanisms with ER showing novel triphasic association behavior.

This study shows that the RNA-binding selectivity of hnRNP U's RGG/RG motifs is reduced by the disordered region, leading to broad RNA interactions.

This study shows Spen binds to endogenous retroviral RNAs and recruits chromatin silencing machinery, linking RNA-mediated retrovirus silencing to X chromosome inactivation.