Rebecca Danner

This study shows that folic acid polyglutamylation activates MAP2K5 signaling to promote adipocyte lipid breakdown, revealing a novel role for folate in lipid homeostasis.

The paper shows that gut microbiota-derived folinic acid suppresses colorectal cancer progression by inhibiting calpain-2 and stabilizing E-cadherin.

The paper identifies a gut microbial metabolite of methotrexate that alleviates gut inflammation by promoting mitochondrial STAT3 signaling.

This paper shows that HLA-DR-expressing fibroblast-like synoviocytes can present Lyme autoantigens and activate CD4+ T cells when stimulated with IFN-gamma and Borrelia burgdorferi.