Thomas Mitchell Schmidt

This study isolates and characterizes microbiota from human pancreatic tumors and small intestine, revealing how a Klebsiella oxytoca strain affects the tumor microenvironment and therapy response.

This paper introduces a coculture model that simulates oral oxygen gradients to study microbial-host interactions and antibiotic efficacy.

The paper co-cultures Bifidobacterium longum with human colonic epithelium and finds reduced inflammation and changes in gene expression related to barrier function and cellular energetics.

This study uses human intestinal organoids to show microbial colonization induces complex physiological changes in immature human epithelium, including antimicrobial peptide production and mucus maturation.