PhysiologybioRxivPreprint
Corticosteroids elevate intraocular pressure through suppression of TREK-1 signaling
Sarah N. Redmon, Oleg V. Yarishkin, Christopher N. Rudzitis…·David Križaj
This study shows corticosteroids increase intraocular pressure by suppressing TREK-1 channels in trabecular meshwork cells, leading to ocular hypertension, which can be counteracted by TREK-1 agonists.
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