Elina Ikonen

This study identifies Adig as a regulator of lipid droplet formation by stabilizing the dodecameric seipin complex, leading to increased fat mass and thermogenesis in mice.

This study shows that Sac1 regulates Golgi V-ATPase assembly by controlling TGN membrane composition through lipid exchange, leading to Golgi fragmentation and impaired glycosylation.

The paper identifies cholesterol binding to VCAM-1 as a mechanism promoting vascular inflammation by stabilizing VCAM-1 and enhancing immune cell recruitment.

The paper introduces Regression Plane, a tool for continuous phenotypic analysis using machine learning without requiring class labels.