Julie R. McMullen

This study shows that biological sex and nitric oxide synthase inhibition lead to different cardiac responses to cardiometabolic stress in older mice, resulting in distinct HFpEF-like or HFrEF-like phenotypes.

This study shows that removing GM3 gangliosides in cardiomyocytes slightly reduces heart size but does not protect against ischemia-reperfusion injury.

This study investigates the role of B55α in cardiac transcriptome regulation, finding sex-specific effects on cardiac fibrosis and gene expression.

This study uses single-cell multiomic analysis to identify transcriptional circuits driving non-ischemic cardiac fibrosis in mouse and human hearts, showing reversibility of fibrosis-related changes.

This study demonstrates that long-term tissue-specific Cas9 expression in mice does not cause detrimental health effects or metabolic changes, supporting its use for gene-specific studies.