Author

Yow Keat Tham

Baker Heart and Diabetes InstituteORCID 0000-0002-9790-1926Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

Daniel G. DonneriD· 2 shared Helen KiriazisiD· 2 shared Julie R. McMulleniD· 2 shared Natalie A. MellettiD· 2 shared Peter J. MeikleiD· 2 shared Aascha BrowniD· 1 shared Adam C. ParslowiD· 1 shared Akshima Dogra· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersPathology

Daniel G. DonnerORCID

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2 papers

Recent·Most cited

PathologybioRxivPreprintSep 3, 2026

Nitric oxide synthase inhibition and biological sex define different cardiac responses to cardiometabolic stress in older mice.

June Sun, Alejandro Torres, Joshua Hor…·Morag J. Young

This study shows that biological sex and nitric oxide synthase inhibition lead to different cardiac responses to cardiometabolic stress in older mice, resulting in distinct HFpEF-like or HFrEF-like phenotypes.

DOI 10.64898/2026.08.28.747952

mousebulk RNA-seq

𝕏 PostBluesky

PhysiologybioRxivPreprintJul 18, 2026

Ablation of GM3 Gangliosides in cardiomyocytes modestly impacts heart size but does not protect the murine heart against ischemia reperfusion injury

Yow Keat Tham, Daniel G. Donner, Gunes S. Yildiz…·Julie R. McMullen

This study shows that removing GM3 gangliosides in cardiomyocytes slightly reduces heart size but does not protect against ischemia-reperfusion injury.

DOI 10.64898/2026.07.13.738350

mousemetabolomics

𝕏 PostBluesky