Author

Jonas V. Schaefer

University of ZurichORCID 0000-0002-8332-4371Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andreas PlückthuniD· 2 shared Asli KayseriliiD· 1 shared Birgit DreieriD· 1 shared Charles S. UmbaughiD· 1 shared Cihan ErkutiD· 1 shared Claudia ScholliD· 1 shared Dimitri Bieli· 1 shared Dominic HelmiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Andreas PlückthunORCID

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2 papers

Recent·Most cited

Cancer BiologyScience AdvancesPeer-reviewedSep 3, 2025

Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma

Charles S. Umbaugh, Marie Groth, Cihan Erkut…·Claudia Scholl

This study uses T-DARPins to inhibit TBXT in chordoma cells, revealing its regulome and identifying therapeutic vulnerabilities, including sensitivity to JAK2 inhibitors.

5 citations

humanproteomics

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Developmental BiologyNature CommunicationsPeer-reviewedNov 8, 2021

Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc

Shinya Matsuda, Jonas V. Schaefer, Yusuke Mii…·Markus Affolter

The paper shows that Dpp/BMP morphogen dispersal is not strictly required for overall wing patterning and growth in Drosophila, challenging a long-standing dogma.

38 citations

Drosophilaexperimental assay

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