Author

Carolina Filipponi

University of PisaORCID 0009-0002-1529-2862Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell signaling & trafficking· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:metabolism & bioenergetics· 2 Assay:proteomics· 2

Frequent Co-Authors

Michele LaiiD· 4 shared A. De CarliiD· 3 shared Giulia SciandroneiD· 3 shared Elena IaconoiD· 2 shared Fabio FilippiniiD· 2 shared Giulia FreeriD· 2 shared Mauro PistelloiD· 2 shared Roberto AngeliniiD· 2 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersMicrobiology

Michele LaiORCID

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4 papers

Recent·Most cited

PhysiologyJournal of Translational MedicinePeer-reviewedOct 27, 2026

Unconventional Small Molecule MNP-021 Protects Neuronal and Glial Function from Diabetes-Associated Glucotoxicity and Neuroinflammation

A. De Carli, Carolina Filipponi, Beatrice Polini…·Giuseppe Daniele

This paper tests the neuroprotective effects of MNP-021 against diabetes-induced glucotoxicity and neuroinflammation in neurons and glial cells, finding it restores glucose handling, mitochondrial function, and pro-resolving signaling.

DOI 10.1186/s12967-026-09028-7

humanbulk RNA-seq

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MicrobiologybioRxivPreprintJun 24, 2026

Peroxisome dynamics during HSV-1 life cycle in human neurons

Carolina Filipponi, A. De Carli, Iwan Gane…·Michele Lai

This study shows HSV-1 uses peroxisomal metabolism and lipid pathways in human neurons to support its replication and suggests this may contribute to neuronal damage in Alzheimer's disease.

DOI 10.64898/2026.06.23.732381

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintJun 2, 2026

An N-acylphosphatidylethanolamine-LRRK2 axis controls lysosomal homeostasis in Parkinson s disease

Francesca Palese, Carmela Giachino, Sylvie Syan…·Chiara Zurzolo

This study identifies NAPEs as regulators of LRRK2 and lysosomal function in Parkinson's disease, showing that boosting NAPEs reduces LRRK2 activity and clears alpha-synuclein aggregates.

DOI 10.64898/2026.03.19.712902

humanproteomics

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MicrobiologyJournal of Medical VirologyPeer-reviewedJan 24, 2026

N-acylethanolamine acid amidase inhibition reduces SARS-CoV-2 infection in Human Precision cut-lung slices and downregulates NF-kappaB signalling.

Veronica La Rocca, Carolina Filipponi, Viktoria Diesendorf…·Michele Lai

This study shows that inhibiting NAAA reduces SARS-CoV-2 replication in human lung tissue and suppresses NF-kappaB signaling.

DOI 10.1002/jmv.70819

humanbulk RNA-seq

𝕏 PostBluesky