Krishna Prahlad Maremanda

Cigarette smoke aggravates atherosclerosis by promoting the infiltration of inflammasome-primed neutrophils and disrupting macrophage function in lesions

This study shows cigarette smoke aggravates atherosclerosis by promoting inflammasome-primed neutrophil infiltration and impairing macrophage function through S100A8/A9 release.

β2 adrenergic receptors orchestrate neutrophil demargination and recruitment to the ischemic heart following myocardial infarction.

This study identifies β2 adrenergic receptors as key regulators of neutrophil demargination and recruitment to the ischemic heart after myocardial infarction, showing that β2-AR blockers can improve cardiac remodeling.

Disulfiram Protects Against Diet-Induced Obesity by Reprogramming Systemic Lipid Partitioning Independent of GSDMD

This study shows Disulfiram protects against obesity and insulin resistance through GSDMD-independent mechanisms by reprogramming systemic lipid handling.