Peter John Bradley

SCD-dependent lipid metabolism licenses alternative macrophage activation and macrophage plasticity

This study identifies SCD as a lipid metabolic checkpoint that regulates macrophage activation and plasticity by maintaining lipid desaturation balance and preventing pro-inflammatory responses.

Toxoplasma IMC1 is a central component of the subpellicular network and plays critical roles in parasite morphology, replication, and infectivity

This study identifies IMC1 as a critical component of the Toxoplasma gondii inner membrane complex, showing its role in morphology, replication, and infectivity through expression timing, knockout, and interaction analyses.

Function and interactions of a protein bridge between the inner membrane complex and subpellicular microtubules in Toxoplasma gondii

This study identifies IMT1 as a protein linking the inner membrane complex and subpellicular microtubules in Toxoplasma gondii, revealing its role in regulating cytoskeletal interactions.