Author

Autumn Gabrielle York

Howard Hughes Medical InstituteORCID 0000-0002-0331-043XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Kevin J. WilliamsiD· 2 shared Mathias H. SkadowiD· 2 shared Richard Anthony FlavelliD· 2 shared Steven J. BensingeriD· 2 shared Walter K. MoweliD· 2 shared Aimee Wu· 1 shared Alexander H. BedardiD· 1 shared Amara C. Thind· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Kevin J. WilliamsORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SCD-dependent lipid metabolism licenses alternative macrophage activation and macrophage plasticity

Tianheng Hou, R L Watson, Alexander H. Bedard, Wei Yuan Hsieh, Jonathan Quintana, Baolong Su, Amara C. Thind, Juliette N. Uy, Clay F. Semenkovich, Peter John Bradley, Peter Tontonoz, Kevin J. Williams, Autumn Gabrielle York, Steven J. Bensinger

This study identifies SCD as a lipid metabolic checkpoint that regulates macrophage activation and plasticity by maintaining lipid desaturation balance and preventing pro-inflammatory responses.

bioRxiv · May 31, 2026 · PreprintImmunology

FABP5 regulates ether lipid metabolism to ameliorate atopic dermatitis

Mathias H. Skadow, Walter K. Mowel, Holly N. Blackburn, Matthew Z. Madden, Haris Mirza, Fengrui Zhang, Autumn Gabrielle York, Richard Anthony Flavell

This study shows FABP5 regulates ether lipid metabolism, reducing inflammation in atopic dermatitis by modulating platelet activating factor levels.

bioRxiv · Oct 24, 2025 · PreprintImmunology

IL-4 Licenses B Cell Activation Through Cholesterol Synthesis

Holly R. Steach, Autumn Gabrielle York, Jonathan R. Mattingly, Mathias H. Skadow, Shuting Chen, Jun Zhao, Kevin J. Williams, Quan Zhou, Weu-Yuan Hsieh, J. Richard Brewer, Rihao Qu, Justin A. Shyer, Christian Harman, Esen Sefik, Walter K. Mowel, , Richard Anthony Flavell

This study shows IL-4 promotes B cell activation by upregulating cholesterol synthesis, which is essential for ER expansion, cell cycle progression, and proliferation during influenza infection.

bioRxiv · May 13, 2024 · PreprintImmunology