Author

Paige M Mortimer

Intima Bioscience (United States)ORCID 0000-0002-8552-2996Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Alberto Bravo‐BlasiD· 1 shared Beau R. WebberiD· 1 shared Branden S. MoriarityiD· 1 shared Chiara Cerrato· 1 shared Christopher Austin KlebanoffiD· 1 shared Ellie Burns· 1 shared Emil LouiD· 1 shared Florencia CanoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alberto Bravo‐BlasORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

CISH, a novel intracellular immune checkpoint, in comparison and combination to existing and emerging cancer immune checkpoints

Florencia Cano, Alberto Bravo‐Blas, Mathilde Colombé, Chiara Cerrato, Ram Venegalla, Olivier Preham, Ellie Burns, Paige M Mortimer, Nicholas J. Slipek, Matthew J. Johnson, Beau R. Webber, Branden S. Moriarity, Emil Lou, Modassir S. Choudhry, Christopher Austin Klebanoff, Tom Henley

This study shows that deleting CISH enhances T cell anti-cancer functions more than other intracellular checkpoints, improving tumor antigen recognition and killing in CAR-T cells.

bioRxiv · Apr 26, 2025 · PreprintCancer Biology