Author

Gabriele Di Napoli

German Center for Neurodegenerative DiseasesORCID 0000-0002-8552-8909Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Carlo Fiore ViscomiiD· 1 shared Dario BrunettiiD· 1 shared Dina Ivanyuk· 1 shared Maria Jose Perez J.iD· 1 shared Massimo ZevianiiD· 1 shared Mathias JuckeriD· 1 shared Michela DeleidiiD· 1 shared Rawaa Al‐Shaana· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Carlo Fiore ViscomiORCID

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1 paper

Recent·Most cited

Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids

Maria Jose Perez J., Dina Ivanyuk, Vasiliki Panagiotakopoulou, Gabriele Di Napoli, Stefanie Kalb, Dario Brunetti, Rawaa Al‐Shaana, Stephan A. Kaeser, Sabine A. K. Fraschka, Mathias Jucker, Massimo Zeviani, Carlo Fiore Viscomi, Michela Deleidi

This study shows that PITRM1 deficiency in human cerebral organoids leads to Alzheimer's-like pathology, including protein aggregates and tau pathology, while 2D cultures do not show these features.

Molecular Psychiatry · Jul 6, 2020Peer-reviewedNeuroscience