CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signalling to promote expansion of cortical progenitors.
Roxane Van Heurck, Marta Wojno, Ikuo Suzuki, Fausto D. Velez-Bravo, Jérôme Bonnefont, Emir Erkol, Dan Truc Nguyen, Adèle Herpoel, Angéline Bilheu, Catherine A. Ledent, Pierre Vanderhaeghen
This study identifies CROCCP2 as a human-specific gene that enhances cortical progenitor expansion by modulating cilia dynamics and mTOR signalling.
bioRxiv · Jun 17, 2020 · PreprintNeuroscience