Denise C. Fitzgerald

The paper uses spatial transcriptomics to analyze inflammation in multiple sclerosis, identifying unique immune signatures in tertiary lymphoid-like structures.

This study shows that regulatory T cells protect against age-related retinal inflammation and neurodegeneration by preventing retinal pigment epithelium dysmorphology and phagocyte accumulation in aged mice.

This study shows that ageing impairs regulatory T cells' ability to promote remyelination by reducing their capacity to drive oligodendrocyte differentiation and myelination.

The paper identifies myeloid-derived suppressor cells (M-MDSCs) as biomarkers for predicting milder clinical courses in multiple sclerosis.

This study shows that microbiota modulates inflammatory responses during CNS demyelination but has little effect on remyelination in mice.