PERK orchestrates MERCS formation and mitochondrial remodelling promoting physiological adaptations during adaptive UPR signalling
José C. Casas-Martinez, Xia Qin, Penglin Li, María Borja-Gonzalez, Antonio Miranda‐Vizuete, Emma A. McDermott, Peter Dockery, Leo R. Quinlan, Katarzyna Goljanek‐Whysall, Afshin Samali A, Brian McDonagh
This study shows PERK promotes MERCS formation and mitochondrial remodelling during adaptive UPR signalling in myoblasts and C. elegans, enhancing physiological function.
Cell Death and Differentiation · Nov 1, 2025Peer-reviewedCell Biology