Author

Penglin Li

Ollscoil na Gaillimhe – University of GalwayORCID 0000-0003-4440-8457Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Assay:metabolomics· 2

Frequent Co-Authors

Brian McDonaghiD· 4 shared José C. Casas-MartineziD· 4 shared Katarzyna Goljanek‐WhysalliD· 4 shared Antonio Miranda‐VizueteiD· 3 shared Leo R. QuinlaniD· 3 shared Xia QiniD· 3 shared Emma A. McDermottiD· 2 shared Jiwang Tang· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersCell Biology

Brian McDonaghORCID

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4 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 24, 2026

Peroxiredoxin 6 limits mitochondrial peroxidation to prevent mitochondrial ER contact site assembly and inflammatory signalling following adaptive stress

Penglin Li, Yating Zheng, Jiwang Tang…·Brian McDonagh

This study shows PRDX6 limits mitochondrial lipid peroxidation under oxidative stress, preventing MERCS formation and inflammation in both myoblasts and C. elegans.

DOI 10.64898/2026.07.24.740509

humanC. elegans

𝕏 PostBluesky

Cell BiologyCell Death and DifferentiationPeer-reviewedNov 1, 2025

PERK orchestrates MERCS formation and mitochondrial remodelling promoting physiological adaptations during adaptive UPR signalling

José C. Casas-Martinez, Xia Qin, Penglin Li…·Brian McDonagh

This study shows PERK promotes MERCS formation and mitochondrial remodelling during adaptive UPR signalling in myoblasts and C. elegans, enhancing physiological function.

17 citationstop 1%

C. eleganshuman

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMay 13, 2025

Exercise Related microRNAs in C. elegans Regulate Calcium Homeostasis and Mitochondrial Dynamics: Conserved pathways, Divergent mircoRNAs

Xia Qin, Jiwang Tang, José C. Casas-Martinez…·Brian McDonagh

This study identifies exercise-related microRNAs in C. elegans that regulate calcium homeostasis and mitochondrial dynamics, showing conserved pathways but divergent microRNAs across species.

DOI 10.1101/2025.05.13.653755

C. elegansmouse

𝕏 PostBluesky

Molecular BiologyMolecular MetabolismPeer-reviewedAug 6, 2024

Peroxiredoxin 2 Regulates DAF-16/FOXO Mediated Mitochondrial Remodelling in Response to Exercise that is Disrupted in Ageing

Xia Qin, Penglin Li, José C. Casas-Martinez…·Brian McDonagh

This study shows PRDX-2 regulates DAF-16/FOXO-mediated mitochondrial remodelling during exercise, which is disrupted in ageing in C. elegans.

16 citations

C. elegansexperimental assay

𝕏 PostBluesky