Joseph Carroll

Transplantation of human iPSC-derived retinal cells in the cone-dominant Northern tree shrew

This study transplants human iPSC-derived retinal cells into Northern tree shrews and shows improved survival with a complex immunosuppression treatment.

Long-read sequencing with targeted assembly of the opsin locus accurately evaluates genes in expressed positions

This paper evaluates long-read sequencing with targeted assembly for accurately analyzing the opsin gene cluster, showing high concordance and improved detection of color vision deficiencies and carrier status.

Optoretinography in R9AP-bradyopsia reveals the essential role of G-protein signaling in the human cone elongation response

This study uses optoretinography in R9AP-bradyopsia patients to show that G-protein signaling is essential for the human cone elongation response.

BOLD Contrast Response Characteristics of Aberrant Voxels with Bilateral Visual Population Receptive Fields in Human Albinism

The paper investigates BOLD contrast responses in albinism, finding that dual population receptive fields in visual areas V1-V3 show simple summation rather than interaction during simultaneous stimulation.

The Endoplasmic Reticulum Proteostasis Regulator ATF6 is Essential for Human Cone Photoreceptor Development

This study shows ATF6 is essential for human cone photoreceptor development and demonstrates that ATF6 activators can restore cone growth in patient-derived retinal organoids.

Retinal and Cortical Determinants of Cortical Magnification in Human Albinism

This study examines retinal and cortical factors affecting visual acuity in albinism, finding that cortical magnification in albinism is similar to controls despite reduced foveal cone density.

Aberrant Visual Population Receptive Fields in Human Albinism

This study uses fMRI and population receptive field modeling to show that individuals with albinism have dual pRFs and altered hemifield representations in visual cortex, with variability across subjects.

Interocular Symmetry and Repeatability of Foveal Outer Nuclear Layer Thickness in Congenital Achromatopsia

This study assesses the repeatability and interocular symmetry of foveal outer nuclear layer thickness in achromatopsia patients and controls, finding reduced thickness in patients but high symmetry.