Stephan Grabbe

KDM6B inhibition modulates monocyte activation and alleviates IMQ-psoriasis skin inflammation

This paper shows that inhibiting KDM6B reduces monocyte activation and skin inflammation in a psoriasis model by restoring H3K27me3 and suppressing inflammatory gene expression.

EGFL7 promotes immune evasion in glioblastoma by interaction with integrin β2

This study identifies EGFL7 as a driver of immune evasion in glioblastoma by interacting with integrin β2, showing that targeting this axis enhances immunotherapy efficacy.

Constitutive expression of IκBζ promotes tumor growth and immunotherapy resistance in melanoma

This study shows that constitutive IκBζ expression in melanoma promotes tumor growth and immunotherapy resistance by suppressing cytokine production and immune cell recruitment.

Spatially organized inflammatory myeloid-CD8+ T cell aggregates linked to Merkel-cell Polyomavirus driven Reorganization of the Tumor Microenvironment

The paper identifies spatial immune patterns in Merkel cell carcinoma linked to viral status and patient outcomes.