Amena Nabih

This study identifies TF binding sites on the Integrator complex that mediate gene-specific transcription regulation and inducible transcriptional responses.

The paper identifies that only 6% of expressed genes are functionally regulated by miRNAs in mESCs using integrative analysis of transcriptome data and miRNA interaction predictions.

This study identifies the Aquarius/EMB-4 helicase as essential for initiating small RNA-induced co-transcriptional gene silencing in C. elegans by facilitating HRDE-1 complex engagement with nascent transcripts.