Author
University of Massachusetts Chan Medical SchoolORCID 0000-0002-8780-7143Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Krishna Sumanth Ghanta, Zexiang Chen, Aamir Mir…·Craig C. Mello
This study shows that 5' modifications to DNA repair templates enhance precision genome editing efficiency in multiple animal models and human cells.
Gregoriy A. Dokshin, Gregory M. Davis, Ashley Sawle…·Michelle A. Carmell
The paper shows GCNA interacts with Topoisomerase II to resolve DNA-protein crosslinks, maintaining genome stability in germline and early embryos.
Gregoriy A. Dokshin, Krishna Sumanth Ghanta, Katherine M. Piscopo, Craig C. Mello
This paper describes an optimized CRISPR-based genome editing protocol in C. elegans using ssODN and hybrid donors, achieving efficient and reproducible edits for both short and long constructs.