Ashley Sawle

Tissue-resident regulatory T cells exert dualistic anti-tumour and pro-repair function in the exocrine pancreas

This study identifies a rare pancreatic tissue-resident regulatory T cell population that exhibits both anti-tumour and pro-repair functions in the exocrine pancreas.

GCNA interacts with Spartan and Topoisomerase II to regulate genome stability.

The paper shows GCNA interacts with Topoisomerase II to resolve DNA-protein crosslinks, maintaining genome stability in germline and early embryos.

Daedalus and Gasz recruit Armitage to mitochondria, bringing piRNA precursors to the biogenesis machinery

The paper identifies Daedalus and Gasz as mitochondrial factors that recruit Armitage to mitochondria, facilitating piRNA precursor processing by linking nuage/Yb-body and mitochondrial biogenesis machinery.