A predominately pulmonary activation of complement in a mouse model of severe COVID-19
Peter J. Szachowicz, Christine Wohlford-Lenane, Cobey J. H. Donelson, Shreya Ghimire, Andrew L. Thurman, Biyun Xue, Timothy J. Boly, Abhishek Verma, Leila MašinoviĆ, Jennifer Bermick, Tayyab Rehman, Stanley M. Perlman, David Kyle Meyerholz, Alejandro A. Pezzulo, Yuzhou Zhang, , Paul B. McCray
This study identifies pulmonary complement activation in a mouse model of severe COVID-19, showing local complement production and its role in lung injury.
iScience · Feb 1, 2025Peer-reviewedImmunology