Author

Uxía Gestal Mato

Goethe University FrankfurtORCID 0000-0002-6004-7420Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Ivan ĐikićiD· 2 shared Adriana Covarrubias‐PintoiD· 1 shared Alberto CristianiiD· 1 shared Alexis GonzáleziD· 1 shared Aparna Viswanathan AmmanathiD· 1 shared Belinda CampiD· 1 shared Christian Andreas HübneriD· 1 shared Chun KewiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Ivan ĐikićORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

TBK1 restricts IRGQ-mediated autophagy

Uxía Gestal Mato, Pauline Lascaux, Sergio Alejandro Poveda Cuevas, Alberto Cristiani, Belinda Camp, Mahyar Aghapour, Aparna Viswanathan Ammanath, Ramachandra M. Bhaskara, Ivan Đikić, Lina Herhaus

This study identifies TBK1 as a regulator of IRGQ-mediated autophagy by disrupting the IRGQ-GABARAPL2 complex through phosphorylation of GABARAPL2.

Nature Communications · May 13, 2026Peer-reviewedBiochemistry

Intracellular lipopolysaccharide binds RETREG1/FAM134B to regulate ER remodeling upon bacterial infection

Yi‐Lin Cheng, João Mello-Vieira, Adriana Covarrubias‐Pinto, Alexis González, Santosh Kumar Kuncha, Chun Kew, K. Zhang, Muhammad Awais Afzal, Nour Diab, Sophia Borchert, Siou-Ying Hong, Timothy Chun Huang, Wenbo Chen, Uxía Gestal Mato, Mathias Walter Hornef, , Ivan Đikić

This study shows that bacterial LPS binds RETREG1 to induce ER remodeling and enhance antibacterial defense through ERphagy.

Autophagy · May 12, 2026Peer-reviewedCell Biology