Author

Isabelle Bernard‐Pierrot

Centre National de la Recherche ScientifiqueORCID 0000-0002-8967-5092Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Alice BlondeliD· 1 shared Ana Cayuela LópeziD· 1 shared Aurélien de ReynièsiD· 1 shared Christian PfisteriD· 1 shared Clarice S. GroeneveldiD· 1 shared Clémentine Krucker· 1 shared Eduardo ZarzuelaiD· 1 shared Eleonora LapiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Alice BlondelORCID

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2 papers

Recent·Most cited

Deep Learning Bridges Histology and Transcriptomics to Predict Molecular Subtypes and Outcomes in Muscle-Invasive Bladder Cancer

Alice Blondel, Clémentine Krucker, Valentin Harter, Melissa Da Silva, Clarice S. Groeneveld, Aurélien de Reyniès, Maryam Karimi, Simone Benhamou, Isabelle Bernard‐Pierrot, Christian Pfister, Stéphane Culine, Yves Allory, Thomas Walter, Jacqueline Fontugne

This paper develops a deep learning model to predict molecular subtypes and outcomes in muscle-invasive bladder cancer using histopathological images instead of RNA sequencing.

bioRxiv · Oct 23, 2025 · PreprintCancer Biology

STAG2 cohesin cooperates with DREAM to maintain quiescence and suppress tumourigenesis in the urothelium

Maria Ramal, Eleonora Lapi, Mark Kalisz, Jaime Martínez de Villarreal, Meritxell Novillo-Font, Miriam Marqués, Eduardo Zarzuela, Marta Isasa, Osvaldo Graña‐Castro, Jianming Xu, Ana Cayuela López, François Radvanyi, Mireia Novell, Jorge Luis Martinez-Torrecuadrada, Marı́a José Barallobre, , Francisco X. Real

This study shows that STAG2 cohesin works with DREAM to maintain quiescence and prevent tumor formation in urothelial cells by regulating chromatin structure and cell cycle control.

bioRxiv · Oct 10, 2025 · PreprintCancer Biology