Osvaldo Graña‐Castro

This study shows CDC14 phosphatases regulate adipogenesis by dephosphorylating PPARγ, improving glucose metabolism and preventing obesity in mice.

This study shows that STAG2 cohesin works with DREAM to maintain quiescence and prevent tumor formation in urothelial cells by regulating chromatin structure and cell cycle control.

The paper identifies CD74+ microglia/macrophages driven by MIF as clinically relevant subpopulations in brain metastasis and other CNS disorders, showing their role in disease progression and therapeutic targeting potential.

This study identifies PIEZO1 as an oncogene in glioma that promotes astrocyte reactivity and is associated with worse prognosis in male patients.

This study identifies Hnrnpk as a master regulator of nucleolar stress and ribosome impairment, linking nucleolar abnormalities to aging and bone marrow failure.

The paper investigates how 3D chromatin structure and chromatin environment influence DNA replication origin activation efficiency in mouse embryonic stem cells under stress and control conditions.