Yoshitsugu Aoki

This study examines Ca2+ dynamics in muscle stem cells during regeneration, finding increased fluctuations in activated cells mediated by mechanosensitive ion channels.

eSkip2 identifies effective exon-skipping ASO target regions by integrating genomic context and splicing perturbations, outperforming exon-restricted models in prioritizing active regions.

This study identifies MBOAT2 as a key enzyme that limits PUFA in PC and promotes muscle regeneration in dystrophic and neonatal muscle.

This paper introduces CRISPR MiRAGE, a miRNA-sensing guide RNA system that enables tissue-specific gene editing by modulating CRISPR activity based on miRNA signatures.

The paper develops a two-photon imaging method to study neural activity in the NTS during VNS and hormone exposure, revealing insights into vagus-NTS pathway function.

This study evaluates the anti-inflammatory and anti-fibrotic effects of N-163 β-glucan in mdx dystrophic mice, showing reduced fibrosis and inflammation markers.