Author

Alice Butler

Washington University in St. LouisORCID 0000-0002-9079-7812Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Assay:electrophysiology· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Karl L. MaglebyiD· 2 shared Lawrence SalkoffiD· 2 shared Yanyan GengiD· 2 shared Alexander Zhang· 1 shared Bill Hao WangiD· 1 shared Celia Maria SantiiD· 1 shared Chinwendu AmazuiD· 1 shared Ethan Li· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Karl L. MaglebyORCID

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3 papers

Recent·Most cited

SLO2.1/NALCN Functional Complex Activity in Mouse Myometrial Smooth Muscle Cells During Pregnancy.

Juan José Ferreira, Lindsey N. Kent, Ronald McCarthy, Alice Butler, Xiaofeng Ma, Nikita Peramsetty, Chinwendu Amazu, Alexander Zhang, Grace C. Whitter, Ethan Li, Sarah K. England, Celia Maria Santi

This study investigates the role of the SLO2.1/NALCN complex in regulating mouse myometrial smooth muscle cell membrane potential across pregnancy, finding its activity decreases as pregnancy progresses.

Journal of Cellular Physiology · Apr 1, 2025Peer-reviewedPhysiology

BK channels of five different subunit combinations underlie the de novo KCNMA1 G375R channelopathy

Yanyan Geng, Ping Li, Alice Butler, Bill Hao Wang, Lawrence Salkoff, Karl L. Magleby

This study investigates the functional effects of a de novo KCNMA1 G375R mutation in BK channels by analyzing five subunit combinations, revealing gain-of-function and loss-of-function phenotypes.

bioRxiv · Dec 22, 2021 · PreprintNeuroscience

Coupling of Ca2+ and voltage activation in BK channels through the αB helix/voltage sensor interface

Yanyan Geng, Zengqin Deng, Guohui Zhang, Gonzalo Budelli, Alice Butler, Peng Yuan, Jianmin Cui, Lawrence Salkoff, Karl L. Magleby

This study investigates how the B helix/voltage sensor interface in BK channels couples Ca2+ and voltage activation, showing its role in transducing both signals to pore opening.

Proceedings of the National Academy of Sciences · Jun 8, 2020Peer-reviewedNeuroscience