Carolina B. Meloto

Paradoxical Phenotype of Fibromyalgia Neutrophils with Elevated Baseline Inflammation but Blunted Response to Stimulation

The paper identifies a paradoxical inflammation state in FM neutrophils that are unresponsive to LPS, linked to NF-κB suppression, and suggests bryostatin as a potential therapeutic target.

A MULTI-TRAIT APPROACH IMPROVES POLYGENIC RISK SCORES FOR CHRONIC BACK PAIN ACROSS POPULATION-BASED AND CLINICALLY ASCERTAINED SAMPLES

This paper improves polygenic risk scores for chronic back pain by combining multiple traits, showing better performance in clinical samples.

Fibromyalgia patients with high levels of anti-satellite glia cell IgG antibodies present with more severe symptoms

This study finds that fibromyalgia patients with higher anti-satellite glia cell IgG antibodies have more severe symptoms, suggesting these antibodies may contribute to disease severity.