Hao Huang

Charting sex divergence in the human brain across the lifespan

This paper constructs sex-specific lifespan brain charts using neuroimaging data from 59,915 individuals, revealing dynamic sex differences in brain development and improving detection of neuropsychiatric abnormalities.

Competing Programs Shape Cortical Sensorimotor-Association Axis Development

The paper presents the MIND model, showing that competing induction and exclusion programs shape the sensorimotor-to-association axis in the neocortex across species.

A layered standards framework for integrating single-cell and spatial omics data into brain cell atlases

This paper introduces a standards framework for integrating single-cell and spatial omics data into brain cell atlases, enabling interoperable and reusable knowledge-ready resources.

Highly replicable multisite patterns of adolescent white matter maturation

The paper presents a curated dataset of processed diffusion MRI data from the ABCD Study, showing that specific diffusion metrics are sensitive to adolescent white matter development and robust to image quality variation.

Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications

The paper describes improvements in diffusion MRI processing for the HBCD study, introducing new software and observing developmental patterns in brain data.

The maturation of infant and toddler visual cortex neural activity and associations with fine motor performance

This study examines the development of visual evoked responses in infants and toddlers using MEG, finding nonlinear changes in latency and amplitude and associations with fine motor skills.

Molecular Specification of Claustro-Amygdalar and Paleocortical Neurons and Connectivity

This study identifies SOX4, SOX11, and TFAP2D as critical regulators of ventropallial excitatory neuron development and PFC connectivity in mice, with conserved roles in humans.

Spatiotemporal cerebral blood flow dynamics underlies emergence of the limbic-sensorimotor-association cortical gradient in human infancy

The paper identifies a spatiotemporal pattern of cerebral blood flow in infants that correlates with cortical specialization and developmental functioning.

Development of neonatal connectome dynamics and its prediction for cognitive and language outcomes at age 2

This study examines neonatal brain connectome dynamics using resting-state fMRI and finds that these dynamics predict cognitive and language outcomes at age 2.

Development of Sensorimotor-Visual Connectome Gradient at Birth Predicts Cognitive Outcomes at 2 Years of Age

The paper shows that a sensorimotor-to-visual connectome gradient present at birth predicts cognitive outcomes at 2 years of age in preterm and term babies.

Infant brain regional cerebral blood flow dynamics supporting emergence of vital functional networks

This study investigates infant cerebral blood flow dynamics and their role in the emergence of functional networks like the default-mode network using multi-modal MRI.

Diffusion-MRI-based regional cortical microstructure at birth for predicting neurodevelopmental outcomes at 2-year-olds

The paper uses diffusion MRI to predict 2-year-old neurodevelopmental outcomes from neonate cortical microstructure using support vector regression.

Neuroanatomical underpinning of diffusion kurtosis measurements in the cerebral cortex of healthy macaque brains

This study correlates diffusion kurtosis imaging (DKI) measurements with neurofilament density in macaque brains, showing higher MK and ND in prefrontal/precentral-postcentral cortex compared to temporal cortex.

Regularized-Ncut: Robust and homogeneous functional parcellation of neonate and adult brain networks

This paper introduces RNcut, a method for robust and homogeneous brain network parcellation in neonates and adults, showing improved performance over existing methods in simulated and real rs-fMRI data.

Structural network maturation of the preterm human brain

This study examines structural network maturation in preterm and term-born neonates using diffusion MRI, finding faster increases in hub and rich-club connectivity during the third trimester.