Isha A. Walawalkar

Splicing of ultraconserved poison exons controls mitotic fidelity and stem cell viability

This study shows that ultraconserved poison exons regulate mitotic splicing fidelity and stem cell viability by controlling SR protein levels and splicing networks.

The miR-144/Hmgn2 regulatory axis orchestrates chromatin organization during erythropoiesis

This study identifies miR-144 and Hmgn2 as key regulators of chromatin condensation during erythropoiesis, showing their conserved role from fish to humans.

Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elements

The paper identifies structural variants in 20 mouse strains using long-read sequencing, revealing transposable elements' role in chromatin remodeling and gene expression in mESCs.

Transposable element-mediated rearrangements are prevalent in human genomes

The paper identifies transposable element-mediated rearrangements (TEMRs) in human genomes, showing they are enriched in genic regions and can create risk alleles.