Author

Yunkang Lin

Broad InstituteORCID 0000-0002-9182-8158Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Aidan Cruickshank· 1 shared Alan Y. Baez VazqueziD· 1 shared Alexander O. ManniD· 1 shared Alicia LaiiD· 1 shared Andrea ShehajiD· 1 shared Andrew Mark BrunneriD· 1 shared Ashwin V. KammulaiD· 1 shared Carla F. KimiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Aidan Cruickshank

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Type I interferon primes the alveolar epithelium to receive reparative signals from tissue-resident macrophages

Alan Y. Baez Vazquez, Daisy A. Hoagland, Alexander O. Mann, Yunkang Lin, Susanna M. Dang, Max Hauptschein, Louison Thorens, Shahinoor Begum, M. Castro, Patricia Rodríguez-Morales, Alicia Lai, Irving Barrera, Dawei Sun, Andrea Shehaj, Fei Chen, , Ruth A. Franklin

The paper shows that type I interferon primes alveolar epithelial cells for regeneration by enhancing their response to reparative signals from tissue-resident macrophages after viral infection.

bioRxiv · Jun 12, 2026 · PreprintImmunology

Sialylated CD43 is a glyco-immune checkpoint for macrophage phagocytosis

Jooho Chung, Mounica Vallurupalli, Sarah Noel, Gail Schor, YuhJong Liu, Celeste Nobrega, Jonathan Perera, Ewa Wrona, Margaret Hu, Yunkang Lin, David Wei Wu, Maria Saberi, Ilario Scapozza, Aidan Cruickshank, Elliot C. Woods, , Robert T. Manguso

The paper identifies CD43 as a glyco-immune checkpoint that inhibits human macrophage phagocytosis, showing that O-linked glycosylation and sialylation pathways regulate this process in AML.

bioRxiv · May 5, 2025 · PreprintCancer Biology