Jennifer M. Lin

Loss Of Chromodomain of Male-Specific Lethal 3 (MSL3) Does Not Affect Spermatogenesis In Rodents

The paper investigates the role of Msl3 in meiotic entry in mice and finds that its loss-of-function does not disrupt spermatogenesis.

Sociosexual behavior requires both activating and repressive roles of Tfap2e/AP-2ε in vomeronasal sensory neurons

The paper shows that AP-2ε reprograms vomeronasal sensory neurons and their behaviors by controlling gene expression, bypassing cellular plasticity restrictions.

Notch signaling determines cell-fate specification of the two main types of vomeronasal neurons of rodents.

This study identifies Notch1 receptor and Dll4 ligand differential expression in neuronal precursors and shows their role in determining the binary dichotomy of vomeronasal neuron types in mice.

MSL3 coordinates a transcriptional and translational meiotic program in female Drosophila

This study identifies MSL3 as a master regulator coordinating transcription and translation during meiosis in female Drosophila and shows its conserved role in mouse spermatogenesis.

Automated quantification of vomeronasal glomeruli number, size, and color composition after immunofluorescent staining

The paper develops a Python program to automate the quantification of glomeruli features in mouse olfactory bulbs, validated for efficiency and accuracy in genetic studies.

Gli3 regulates vomeronasal neurogenesis, olfactory ensheathing cell formation, and GnRH-1 neuronal migration.

This study shows Gli3 is critical for olfactory ensheathing cell development and GnRH-1 neuronal migration, and identifies a GLI3 mutation in a Kallmann syndrome patient.

Smad4 signaling establishes the somatosensory map of basal vomeronasal sensory neurons

This study shows that Smad4 signaling is essential for the development, function, and circuit formation of basal vomeronasal sensory neurons.

The transcription factor Tfap2e/AP-2ε plays a pivotal role in maintaining the identity of basal vomeronasal sensory neurons

This study shows that AP-2ε maintains basal vomeronasal sensory neuron identity by preventing apical gene expression and highlights their differentiation plasticity.

Olfactory and vomeronasal innervation of the olfactory bulbs are not essential for GnRH-1 neuronal migration to the brain.

This study shows that proper olfactory bulb development and olfactory/vomeronasal axonal connections are not required for GnRH-1 neuronal migration to the hypothalamus.