Author

Olivia Ettlin

California Institute of TechnologyORCID 0000-0002-9243-9752Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Alex BurriD· 2 shared Isabel Nadine GoronzyiD· 2 shared Mario R. BlancoiD· 2 shared Mitchell GuttmaniD· 2 shared Allen W CheniD· 1 shared Amy Y. ChowiD· 1 shared Andrew A. PereziD· 1 shared Benjamin L. EmertiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenomics

Alex BurrORCID

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2 papers

Recent·Most cited

ChIP-DIP: A multiplexed method for mapping hundreds of proteins to DNA uncovers diverse regulatory elements controlling gene expression

Andrew A. Perez, Isabel Nadine Goronzy, Mario R. Blanco, Benjamin T. Yeh, Jimmy K. Guo, Carolina S. Lopes, Olivia Ettlin, Alex Burr, Mitchell Guttman

ChIP-DIP enables simultaneous mapping of hundreds of regulatory proteins to DNA, revealing diverse regulatory elements and their functional activity.

Nature Genetics · Nov 25, 2024Peer-reviewedGenomics

3D genome organization around nuclear speckles drives mRNA splicing efficiency

Prashant Bhat, Amy Y. Chow, Benjamin L. Emert, Olivia Ettlin, Sofia A. Quinodoz, Mackenzie M. Strehle, Yodai Takei, Alex Burr, Isabel Nadine Goronzy, Allen W Chen, Wesley Huang, Jose Lorenzo M. Ferrer, Elizabeth Soehalim, Say-Tar Goh, Tara Chari, , Mitchell Guttman

The paper shows that gene proximity to nuclear speckles increases spliceosome binding and co-transcriptional splicing efficiency, highlighting the role of 3D genome organization in mRNA splicing.

Nature · May 8, 2024Peer-reviewedMolecular Biology