Mean-Hwan Kim

Human Neocortical Glutamatergic Neurons Revealed Through Multimodal Profiling

The paper integrates multimodal data to characterize human neocortical glutamatergic neurons, revealing morphoelectric properties that distinguish transcriptomic subclasses and highlight species-specific differences.

Convergent Control of NREM Sleep and Anesthesia by Prefrontal Layer 5 Extratelencephalic Neurons

This study identifies prefrontal cortical neurons that regulate both NREM sleep and anesthesia by modulating their activity and connectivity.

Functional selectivity and specific connectivity of inhibitory neurons in primary visual cortex

The paper shows that inhibitory neurons in mouse primary visual cortex selectively connect with excitatory neurons based on response similarity, stabilizing network dynamics and enabling subnetwork competition.

Target cell-specific synaptic dynamics of excitatory to inhibitory neuron connections in supragranular layers of human neocortex

The paper investigates target cell-specific synaptic dynamics between excitatory and inhibitory neurons in human neocortex, finding similarities to rodent studies.

Local Connectivity and Synaptic Dynamics in Mouse and Human Neocortex

The paper presents a synaptic physiology dataset and analysis platform to study cortical microcircuit structure and synaptic properties in mouse and human neocortex, revealing layer-dependent connectivity and subclass-specific dynamics.

Temporal learning of bottom-up connections via spatially nonspecific top-down inputs

This study uses network models to show that nonspecific top-down inputs can regulate low-order area responses by providing temporal information, aiding in the learning of bottom-up connections.

Human cortical expansion involves diversification and specialization of supragranular intratelencephalic-projecting neurons

The paper identifies transcriptomic diversity in human supragranular neurons and links it to functional specialization and disease vulnerability.

Exclusive functional subnetworks of intracortical projection neurons in primary visual cortex

The paper investigates how projection neurons in primary visual cortex connect locally and find that target specificity constrains local connectivity independently of response similarity.