Elina Mäntylä

Deep Invaginations of Nuclear Envelope Coordinate Spatial Organization of Chromatin in Epithelium

The paper identifies deep nuclear envelope invaginations (DINEs) in epithelial cells, showing they organize chromatin and gene activity in response to mechanical cues like crowding and tissue maturation.

Viscoelasticity driven deformation dynamics of the substrate affect mechanically induced Ca2+ signals

This study shows that substrate viscoelasticity influences how cells sense mechanical deformation through calcium signals, with stiff substrates producing stronger responses and distinct force dynamics.

Iterative immunostaining combined with expansion microscopy and image processing reveals nanoscopic network organization of nuclear lamina

The paper develops an iterative immunostaining method combined with expansion microscopy and image processing to enhance super-resolution imaging of nuclear lamina structures.