MacRae F. Linton

This study shows that menopause hormone treatment (E2) reduces atherosclerosis in young mice but not older mice, due to age-related changes in inflammation and estrogen receptor signaling.

This study shows that N-aldehyde modified phosphatidylethanolamines (NAMPs) inhibit efferocytosis and are elevated under oxidative stress conditions.

The paper investigates how post-transcriptional modifications on tRNA fragments in HDL affect atherosclerosis by altering immune signaling and macrophage activation.

This study shows that targeting liver epsins reduces atherosclerosis by preventing PCSK9-mediated LDLR degradation and improving LDL-C clearance.

The paper identifies genetic risk factors for hypertriglyceridemia in African ancestry populations using whole genome sequencing and electronic health records.

The paper investigates how HDL binds to single-stranded small RNAs through interactions with apoA-I, revealing mechanisms that may enable extracellular RNA communication.

This study identifies genetic risk factors for major depressive disorder and loneliness as predictors of coronary artery disease risk, particularly in women.

The paper introduces TIGER, a pipeline for analyzing extracellular small RNAs, demonstrating its ability to identify sRNAs on lipoproteins and in biofluids with high accuracy.