Tamara Basta

Synaptotagmin isoforms differentially regulate glutamate and GABA release in the lateral habenula

This study identifies Synaptotagmin-2 and Synaptotagmin-3 as distinct calcium sensors for glutamatergic and GABAergic release in lateral habenula neurons.

N-Linked Glycosylation as a Driver of Tau Pathology and Neuronal Transmission

This study investigates how N-linked glycosylation affects Tau propagation and neuronal uptake by analyzing glycan site and structure effects on Tau-polyanion binding and seeding.

Synaptophysin is a β-Amyloid Target that Regulates Synaptic Plasticity and Seizure Susceptibility in an Alzhiemer’s Model

This study shows that Aβ42 binds to synaptophysin, disrupting its function and leading to impaired neurotransmission and increased seizure susceptibility in an Alzheimer’s model.