Rainer A. Böckmann

MemBack reconstructs atomistic lipid structures from coarse-grained simulations with high accuracy and preserves structural organization across resolutions.

The paper uses simulations to show that lipid-type asymmetry, not phospholipid-number imbalance, is sufficient to reproduce key physical properties of plasma membranes.

This study uses molecular dynamics simulations to show that membrane composition significantly affects the pKa of aminolipids in lipid nanoparticles, influencing their pH-dependent behavior and membrane remodeling.

This study uses CpHMD simulations to analyze pH-driven phase transitions in lipid nanoparticles, revealing how pKa shifts affect structure and mRNA delivery.

The paper investigates glycocalyx dynamics using interferometric scattering microscopy and finds a strong correlation between glycan structure and system dynamics.

This paper applies constant-pH MD simulations to study pH-dependent behavior of cationic ionizable lipids in lipid nanoparticles, focusing on their apparent pKa and implications for drug delivery.

This study shows that DJ-1 metabolites GA and DL can rescue fertility and mitochondrial dysfunction in multiple species, with GA having broader effects across models.