Sachi Inagaki

Mechanical control of the insect extracellular matrix nanostructure

The paper investigates how ZPD proteins in Drosophila regulate nanopore formation in cuticular structures through mechanical forces.

Endoplasmic reticulum patterns insect cuticle nanostructure

The paper reveals how the endoplasmic reticulum (ER) is repurposed via autophagy to form nanopores in Drosophila olfactory organs, controlled by the Gox protein.

Osiris gene family defines the cuticle nano-patterns of Drosophila

The paper identifies Osiris genes as key regulators of cuticle nanostructures in Drosophila, showing their expression in cuticle-secreting cells and their role in shaping specific nano-patterns.

Nanopore formation in the cuticle of an insect olfactory sensillum

The paper identifies an insect-specific endosomal protein involved in forming nanopores in the cuticle, essential for odor detection.

Trynity controls epidermal barrier function and respiratory tube maturation in Drosophila by modulating apical extracellular matrix nano-patterning

This study identifies Trynity as a conserved aECM protein essential for epidermal barrier function and tracheal tube maturation in Drosophila by modulating apical extracellular matrix nano-patterning.

Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis

This study identifies Shavenbaby as a novel Hippo pathway effector critical for adult stem cell survival by activating DIAP1 to prevent apoptosis in Drosophila renal stem cells.