Author

Sven Vilain

Istanbul Medipol UniversityORCID 0000-0002-9166-2792Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 2 Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:Drosophila· 2 Approach:benchmark study· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Nils SchoovaertsiD· 2 shared Patrik VerstrekeniD· 2 shared Sabine KueneniD· 2 shared Ulrike PechiD· 2 shared Adekunle T. BademosiiD· 1 shared Antonio OrtegaiD· 1 shared Asal Ghaffari ZakiiD· 1 shared Ayse KiliciD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Nils SchoovaertsORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Switching ON Hydrogen Sulfide: A Chemogenetic Toolkit for Spatially Resolved H2S Manipulation

Asal Ghaffari Zaki, Seyed Mohammad Miri, Emre Vatandaşlar, Sven Vilain, Esra Nur Yi̇ği̇t, Mehmet Şerif Aydın, Muhammed İkbal Alp, Emrah Eroğlu

This paper benchmarks two enzymes for controlled H2S production, finding that stDCyD generates only H2S while mDAAO also produces hydrogen peroxide.

bioRxiv · May 12, 2025 · PreprintBiochemistry

Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across 5 fly Parkinsonism models

Ulrike Pech, Jasper Janssens, Nils Schoovaerts, Sabine Kuenen, Carles Calatayud, Sandra F. Gallego, Samira Makhzami, Gert J. Hulselmans, Suresh Kumar Poovathingal, Kristofer Davie, Adekunle T. Bademosi, Jef Swerts, Sven Vilain, Stein Aerts, Patrik Verstreken

The paper identifies synaptic dysfunction in cholinergic projection neurons as an early indicator of Parkinsonism across multiple fly models and links it to olfactory dysfunction and dopaminergic decline.

eLife · Apr 3, 2025Peer-reviewedNeuroscience

Development of a Robust Gel-Free 3D Culture System for Generating Spheroids from Axolotl Blastema Cells

Zeynep Aladağ, Safiye Serdengeçti, Sven Vilain, Gürkan Öztürk

This paper develops a gel-free 3D culture system for axolotl blastema cells that maintains cell identity and functionality, enabling extra digit formation upon transplantation.

bioRxiv · Aug 29, 2024 · PreprintMolecular Biology

Behavioral screening defines three molecular Parkinsonism subgroups in Drosophila

Natalie Kaempf, Jorge S. Valadas, Pieter Robberechts, Nils Schoovaerts, Roman Praschberger, Antonio Ortega, Ayse Kilic, Dries Chabot, Ulrike Pech, Sabine Kuenen, Sven Vilain, El‐Sayed Baz, Jeevanjot Singh, Jesse J. Davis, Sha Liu, Patrik Verstreken

The paper identifies three molecular subgroups of parkinsonism in Drosophila using behavioral screening and machine learning, each linked to distinct cellular pathways.

bioRxiv · Aug 27, 2024 · PreprintNeuroscience