Nils Schoovaerts

The paper shows that single-molecule bouncing at a presynaptic interface enables protein enrichment without slowing diffusion.

This study shows that Pink1 loss in Drosophila disrupts ensheathing glia, leading to dopaminergic synapse loss, and identifies vesicle trafficking factors as potential therapeutic targets.

This study establishes an adult-onset Drosophila model of tauopathy, revealing sex-specific effects on survival and behavior and identifying genetic modifiers of tau-induced dysfunction.

The paper identifies synaptic dysfunction in cholinergic projection neurons as an early indicator of Parkinsonism across multiple fly models and links it to olfactory dysfunction and dopaminergic decline.

The paper identifies three molecular subgroups of parkinsonism in Drosophila using behavioral screening and machine learning, each linked to distinct cellular pathways.

The paper shows Drosophila melanogaster resist trans-synaptic spread of human tau, suggesting they are not suitable for screening tau propagation modifiers.

The paper identifies molecular signatures of neuronal vulnerability to α-synuclein and tau toxicity, showing differential susceptibility independent of expression levels.

The paper shows how EndophilinA couples calcium influx to synaptic autophagy and identifies a Parkinson-risk mutation that disrupts this process.